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Imikhiqizo

I-asidi ye-Guanidinoacetic

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Imininingwane yomkhiqizo

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Amathegi womkhiqizo

Izinkomba zomzimba zomkhiqizo
I-Guanidineacetic acid (GAA) Eyaziwa nangokuthi i-acetate ye-guanidine;
Ifomula Yamamolekhula: C3H7N3O2, I-CAS No.: 352-97-6.
Isimo sokubukeka: umbala omhlophe noma ophuzi opinki, othwala angadala ukuvela kombala, kepha akuthinti ukusebenza komkhiqizo.
Imininingwane yomkhiqizo
I-98% ye-guanidine acetic acid ingasetshenziswa ekudleni kwezilwane ukwakha isimo somzimba ngokushesha, ukuthuthukisa isilinganiso senyama, ukukhuthaza amaprotheni synthesis, ukuthuthukisa ukusebenza kahle kwesilinganiso senyama enciphile. Ngoba i-creatine, isakhi somzimba esibalulekile, ayitholakali ekudleni okumsulwa kwamaprotheni, futhi i-guanidylacetic acid iyisandulela se-creatine synthesis ku-vivo, i-guanidylacetic acid iyasebenza kakhulu ekudleni kwamaprotheni ezitshalo futhi ingashintsha amanye amaprotheni atholakala ezilwaneni njenge isidlo senhlanzi nenyama namathambo.
Indlela yokusebenza: i-guanidylacetic acid iyisandulela se-creatine. I-Creatine phosphate, equkethe amandla amakhulu wokudluliswa kweqembu le-phosphate, itholakala kakhulu kwizicubu zemisipha nezinzwa, futhi iyona mpahla enkulu yokunikezwa kwamandla kwezicubu zemisipha yezilwane. Ukwengezwa kwe-guanidinoacetic acid kwenza umzimba ukhiqize inani elikhulu lezinto zokudlulisa iqembu le-phosphate (phosphocreatine), ngaleyo ndlela unikeze amandla omthombo womsebenzi osebenza kahle wemisipha, ubuchopho, ama-gonads nezinye izicubu, okukhuthaza ukusatshalaliswa kwamandla ezicutshini zemisipha ngokuqhubekayo.


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